SCIENCE & MEDICAL AUTOGRAPHS

These Autographs were collected by my Father over his lifetime! Stowe Vintage will feature Autographs of Hollywood Stars, Political Autographs, President's Autographs, Sports Autographs, Military Autographs, Entertainment Autographs, Authors Autographs, Historical Autographs, and More! Comes with a COA. Contact us at 802-253-7000 or stovint08@gmail.com.

Frederick Sanger, OM, CH, CBE, FRS was born on August 13, 1918. Sanger is an English biochemist and twice a Nobel laureate in chemistry. He is the fourth (and only living) person to have been awarded two Nobel Prizes. Sanger was born in Rendcomb, a small village in Gloucestershire, the second son of Frederick Sanger, a medical practitioner, and his wife, Cicely. He was born on August 13, 1918, and educated at Bryanston School and then completed his Bachelor of Arts in natural sciences from St John's College, Cambridge in 1939. Raised as a Quaker, he learned to abhor violence, and during the Second World War he was a conscientious objector, being allowed to continue his research for a PhD. He originally intended to study medicine, but became interested in biochemistry because some of the leading biochemists in the world were at Cambridge at the time. He completed his PhD in 1943 under A. Neuberger, on lysine metabolism and a more practical problem concerning the nitrogen of potatoes. He went on to discover the structure of proteins, most famously that of insulin protein. He also contributed to the determination of base sequences in DNA. Sanger determined the complete amino acid sequence of insulin in 1955. In doing so, he proved that proteins have definite structures. He began by degrading insulin into short fragments by mixing the trypsin enzyme (that hydrolyses the peptide/amide bonds between amino acids that make up the primary structure of proteins) with an insulin solution. He then undertook a form of chromatography on the mixture by applying a small sample of the mixture to one end of a sheet of filter paper. He passed a solvent through the filter paper in one direction, and passed an electric current through the paper in the opposite direction. Depending on their solubility and charge, the different fragments of insulin moved to different positions on the paper, creating a distinct pattern. Sanger called these patterns “blueprints”. Like human fingerprints, these patterns were characteristic for each protein, and reproducible. He reassembled the short fragments into longer sequences to deduce the complete structure of insulin. Sanger concluded that the protein insulin had a precise amino acid sequence. It was this achievement that earned him his first Nobel prize in Chemistry in 1958. In 1975, he developed the chain termination method of DNA sequencing, also known as the Dideoxy termination method or the Sanger method. Two years later he used his technique to successfully sequence the genome of the Phage Φ-X174; the first fully sequenced DNA-based genome. He did this entirely by hand. This has been of key importance in such projects as the Human Genome Project and earned him his second Nobel prize in Chemistry in 1980, together with Walter Gilbert. The only other laureates to have done so were Marie Curie, Linus Pauling and John Bardeen. He is the only person to receive both prizes in chemistry. In 1979, he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Walter Gilbert and Paul Berg, co-winners of the 1980 Nobel Prize in chemistry. Frederick Sanger retired in 1983. In 1992, the Wellcome Trust and the Medical Research Council founded the Sanger Centre (now the Sanger Institute), named after him. The Sanger Institute, located near Cambridge, England, is one of the world's most important centres for genome research and played a prominent role in sequencing the human genome. Almost his only public utterance in two decades was to put his name to a letter by other UK Nobel laureates protesting about the Iraq war. Referring to his youthful conscientious objection, he said, "I still hate war. That is why I signed that letter". In 2007 the British Biochemical Society was given a grant by the Wellcome Trust to catalogue and preserve the 35 laboratory notebooks in which Sanger recorded his remarkable research from 1958 to 1983. In reporting this matter, Science magazine noted that Sanger, "the most self-effacing person you could hope to meet," now was spending his time gardening at his Cambridgeshire home. Even in retirement Sanger has used his extensive knowledge of DNA to aid modern scientists and academics in their work.

Original Frederick Sanger Autograph, signed on a 3 x 5 inch Index Card. There is a light rust stain where a paper clip had once been. Regular Price - $ 95.00 / Sale Price - $ 44.95.

Sir Oliver Joseph Lodge, FRS, (June 12, 1851 - August 22, 1940), born at Penkhull in Stoke-on-Trent and educated at Adams' Grammar School, was a physicist and writer involved in the development of the wireless telegraph. Lodge, in his Royal Institution lectures ("The Work of Hertz and Some of His Successors") coined the term "coherer." He gained the "syntonic" (or tuning) patent from the United States Patent Office in 1898. He was also credited by Lorentz (1895) with the first published description of the Lorentz contraction hypothesis, in 1893.

Original Oliver Lodge Autograph, signed on Card Stock. Regular Price - $ 300.00 / Sale Price - $ 195.00.

Florence Rena Sabin (November 9, 1871–October 3, 1953) was an American medical scientist. She was a pioneer for women in science; she was the first woman to hold a full professorship at Johns Hopkins School of Medicine, the first woman elected to the National Academy of Sciences, and the first woman to head a department at the Rockefeller Institute for Medical Research. In her retirement years, she pursued a second career as a public health activist in Colorado, and in 1951 received a Lasker Award for this work.

Original Florence R. Sabin Autographed Letter, Signed on The Rockefeller Institute For Medical Research 66th Street and Your Avenue New York Letterhead. Approx. Size 5 1/2 x 8 1/2 - mounted on an album page. Hand Written: Dec. 9, 1933 My Dear Mr. Tricker - I am sorry that I have no photograph but I am sending my autograph - Very Sincerely Yours - Florence R. Sabin Regular Price - $ 1800.00 / Sale Price - $ 795.00.

To the best of our knowledge and belief, Miss Marie Bard of New York City is the only woman living in the United States whose portrait is contained in most every stamp collection in America. Nearly 100,000,000 of her likeness were distributed in 1931 on the Red Cross stamps. That's a mark for some of our movie queens to shoot at. (This was taken from a magazine clipping that was in with my fathers collection) Postmarked Dansville, N.Y. May 21 1931 3 am.

Miss Marie Bard, Artist Model for Red Cross Stamp. Close up view of stamp. The two cent Red Cross stamp commemorated the 50th anniversary of the founding of the American National Association of the Red Cross on May 21, 1881. This stamp was very popular at the time it was issued, and added to the bi-colored design allowing many plate combinations, enough copies were saved that it brings little premium today. However, since it was printed in two steps, at least two panes were released without the red cross on one of the stamps; both stamps are obviously highly prized. First Day sales were in Washington, D.C. and Dansville, New York, the home of the first Red Cross chapter.

Original Marie Bard autograph, signed on envelope. Regular Price - $ 450.00 / Sale Price - $ 195.00.

Joyce Brothers was born October 20, 1927. Brothers is an American psychologist and advice columnist, publishing a daily syndicated newspaper column since 1960. She is professionally known as Dr. Joyce Brothers. In addition to being called upon for her expertise in psychology, she also has done comedic cameo appearances, including on such TV shows as Ellery Queen, Mama's Family, Happy Days, Police Squad, The Naked Gun: From the Files of Police Squad!, Police Woman, Night Court, The Nanny, Frasier, The Andy Dick Show, The Tonight Show starring Johnny Carson, One Life to Live, WKRP in Cincinnati, Mickey Spillane's Mike Hammer, Married... with Children, Entourage, The Simpsons, All That, Kenan & Kel, The Steve Harvey Show, Melrose Place, The Lonely Guy and Late Night with Conan O'Brien. She has also appeared as an occasional celebrity guest on game shows such as Match Game, the 1968 revival of What's My Line?, The Gong Show and Hollywood Squares. She also appeared in a Sunday strip of the comic strip Blondie, where she was referred to by Dagwood Bumstead as "Brother Joyce Doctors". Brothers was the ninth most frequent guest on the Tonight Show when Carson retired.

Original Joyce Brothers Autograph, signed on a 3 x 5 Index Card. Written: Best Wishes Joyce Brothers. There is a note at the bottom of card: after guesting on " The Tonight Show", dated May 7, 1971. Regular Price - $ 75.00 / Sale Price - $ 39.00.

Gerhard Herzberg, PC, CC, FRSC, FRS was born December 25, 1904 – died March 3, 1999. Gerhard was a pioneering physicist and physical chemist, who won the Nobel Prize for Chemistry in 1971. Born in Germany, he fled to Canada in 1935, where he continued his distinguished scientific career. Herzberg's main work concerned atomic and molecular spectroscopy. He is well known for using these techniques that determine the structures of diatomic and polyatomic molecules, including free radicals which are difficult to investigate in any other way, and for the chemical analysis of astronomical objects. Herzberg served as Chancellor of Carleton University in Ottawa, Canada from 1973 to 1980. Original Gerhard Herzberg Autograph, signed on a First Day of Issue Envelope. Postmarked Washington D.C. Oct. 14 1963. Regular Price - $ 85.00 / Sale Price - $ 48.00.